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Autumn 2003, Vol. 2, No. 3

Editor’s Memo   Presenting Highlights from Two Exceptional Meetings on Pulmonary Hypertension Two exceptional meetings this year offered rare opportunities for clinicians involved with pulmonary arterial hypertension to evaluate the progress made in treating this disease. In each case, attendees not only reviewed the progress of recent clinical trials but also looked ahead toward what we can expect in the coming years. Most of this issue is devoted to highlights from the Third World Symposium on Pulmonary Arterial Hypertension, held from June 23 to 25 in Venice, Italy. This group has been the prime mover in developing criteria for the classification and diagnosis of pulmonary hypertension, and the meeting this year once again demonstrated why the various task forces assembled contribute so much to our understanding of the pathophysiology of the disease and recent advances in diagnosis and treatment. I want to express my appreciation for the contributions to this issue of Advances in Pulmonary Hypertension from members of the task force committees who provided summaries from their respective sessions and to Nazzareno Galiè, MD, for enabling us to put together this information. The reports from the physicians convey essential information and highlight key issues discussed. They will give you a sense of the excitement we all shared in Venice as we worked toward a consensus on many topics. As assessment and treatment strategies branch in many directions, it is critical for working groups like this to consolidate our knowledge base and seek a consensus that serves as the basis for new guidelines. The other meeting of major importance was held earlier under the auspices of the National Institutes of Health, in Bethesda, Maryland. The report and interview with the meeting’s chairman, John H. Newman, MD, ranges far and wide over a broad spectrum of topics that will put you on the cutting edge of developments in our field, including priorities for future research. Vic Tapson, MD Editor-in-Chief   Take it With You   Download this issue in PDF   Issue Sponsor Ads   Actelion(PDF) Accredo Therapeutics(PDF)   PHA Announcements   Pulmonary Hypertension Awareness Month 2004 Postdoctoral Fellowship Awards Application Process	Articles   Advances in Pulmonary Hypertension, Autumn 2003, Vol. 2, No. 3 cover close-up Click titles to read stories... Profiles in Pulmonary Hypertension: Cardiologist Nazzareno Galiè: A Guiding Light for Worldwide Consensus on Pulmonary Hypertension If anyone is keeping track of the number of scientific publications on pulmonary arterial hypertension (PAH), pulmonary embolism, chronic heart failure, and heart transplantation authored or coauthored by Nazzareno Galiè, MD, the total has reached more than 280... NIH Conference Charts Future Directions in Identifying Patients at Risk for Primary Pulmonary Hypertension Report is based on information presented at a conference sponsored by the National Institutes of Health (NIH) earlier this year to identify trends in diagnosis and management of the disease... Recapping Highlights from the Third World Symposium on Pulmonary Arterial Hypertension, Venice, Italy, June 23-25, 2003 As the broad range of topics suggests, the Third World Symposium on Pulmonary Arterial Hypertension (PAH) addressed many of the issues of overriding importance to clinicians involved with treatment of the disease... Task Force on Diagnosis and Assessment: Identifying the Most Useful Tools A diagnostic algorithm that is accepted among experienced centers can guide the evaluation of pulmonary hypertension... Overview of Genetics as presented at the PAH Symposium in Venice Medical scientists have achieved three major goals proposed by the 1998 Evian task force on the genetics of pulmonary hypertension... Pathophysiology of Pulmonary Hypertension: Recognizing Triggers of the Disease It is unclear whether the various types of PAH share a common pathogenic mechanism... Report From the Task Force on Medical Treatments The recent clinical trials with novel compounds have produced a tremendous increase of both knowledge and therapeutic options in patients with pulmonary arterial hypertension (PAH)... Acute Vasodilator Testing in PAH Vasoconstriction of pulmonary arteries is recognized as an important component of the pathogenesis of pulmonary arterial hypertension (PAH)... Transplantation and Thromboendarterectomy for Severe Pulmonary Hypertension: Report from the Transplant and Interventions Task Force Recent advances in medical and interventional approaches to the management of patients with pulmonary arterial hypertension (PAH) have had a marked effect on the policy toward referring such patients for transplantation... One-on-One Interview Seeking a Consensus on PH: Challenges Left by the Venice Symposium Clinical Algorithm Diagnosis and Assessment of Pulmonary Hypertension (PDF)
Notes   Editorial Advisory Board Editor-in-Chief Ronald J. Oudiz, MD Associate Professor of Medicine UCLA School of Medicine Director, Liu Center for Pulmonary Hypertension Division of Cardiology Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Torrance, California Immediate Past Editor Vallerie V. McLaughlin, MD Associate Professor of Medicine Director, Pulmonary Hypertension Program University of Michigan Health System Ann Arbor, Michigan Editor-in-Chief Elect Richard Channick, MD Professor of Clinical Medicine Pulmonary and Critical Care Division University of California, San Diego Medical Center San Diego, California Associate Editors Erika Berman Rosenzweig, MD Assistant Professor of Pediatrics Department of Pediatrics Columbia College of Physicians and Surgeons New York, New York Robert Frantz, MD Consultant in Cardiovascular Diseases and Internal Medicine Assistant Professor of Medicine Mayo Clinic College of Medicine Rochester, Minnesota Srinivas Murali, MD, FACC Professor of Medicine Drexel University College of Medicine Director, Division of Cardiovascular Medicine Medical Director, Gerald McGinnis Cardiovascular Institute Allegheny General Hospital Pittsburgh, Pennsylvania Publisher Pulmonary Hypertension Association Jack Stibbs, Board Chair Rino Aldrighetti, President Donica Merhazion, Medical Services Associate Director Publishing Staff Stu Chapman, Executive Editor Susan Chapman, Managing Editor Heidi Green, Associate Editor Gloria Catalano, Production Director Michael McClain, Design Director PHA Office Pulmonary Hypertension Association 801 Roeder Road., St.e 400 Silver Spring, MD 20910 301-565-3004, 301-565-3994 (fax) www.PHAssociation.org Provided with an unrestricted educational grant from Actelion Pharmaceuticals, U.S., Inc. and Accredo Therapeuticss. © 2006 by Pulmonary Hypertension Association and DataMedica. All rights reserved. None of the contents may be reproduced in any form whatsoever without the written permission of PHA. Editorial Offices Advances in Pulmonary Hypertension DataMedica 424 Dune Road Westhampton Beach, NY 11978 Tel: 631-288-7733 Fax: 631- 288-7744 Advances in Pulmonary Hypertension is circulated to cardiologists, pulmonologists, rheumatologists and other selected physicians by the Pulmonary Hypertension Association . The contents of the articles are independently determined ly the Editor and the Editorial Advisory Board. PHA's Scientific Leadership Council Editorial Mission Advances in Pulmonary Hypertension is committed to help physicians in their clinical decision making by informing them of important trends affecting their practice. Analyzing the impact of new findings and covering current information in the peer-reviewed literature, Advances in Pulmonary Hypertension is published four times a year. Advances in Pulmonary Hypertension is the official journal of the Pulmonary Hypertension Association. Each article in this journal has been reviewed and approved by members of the Editorial Advisory Board.   Editorial Board Todd Bull, MD Division of Pulmonary Sciences and Critical Care Medicine University of Colorado Health Sciences Center Denver, Colorado Murali Chakinala, MD Director, Pulmonary Hypertension Clinic Washington University School of Medicine St. Louis, Missouri Kristin Highland, MD Assistant Professor Division of Pulmonary and Critical Care Director, Pulmonary Hypertension Clinic Medical University of South Carolina Charleston, South Carolina Jim Maloney, MD Associate Professor of Pulmonary and Critical Care Medicine University of Colorado Health Sciences Center Denver, Colorado Ioana Preston, MD Assistant Professor of Medicine Tufts - New England Medical Center Boston, Massachusetts Zeenat Safdar, MD Assistant Professor of Medicine Department of Medicine, Pulmonary & Critical Care Section Pulmonary Hypertension Center Baylor College of Medicine Houston, Texas Rajan Saggar, MD Assistant Professor Division of Pulmonary and Critical Care Medicine and Hospitalists David Geffen School of Medicine UCLA Los Angeles, California Robert Schilz, DO, PhD Medical Director of Lung Transplantation and Pulmonary Vascular Disease University Hospital of Cleveland Case Western Reserve University Cleveland, Ohio Francisco Soto, MD, MS Assistant Professor Director, Pulmonary Hypertension Program Medical College of Wisconsin Milwaukee, Wisconsin Roxana Sulica, MD Assistant Professor of Medicine Albert Einstein College of Medicine Director, Beth Israel Pulmonary Hypertension Program Beth Israel Medical Center New York, New York

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