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Spring 2005, Vol. 4, No. 1

Editor’s Memo
 

Passing the Torch: New Editorial Team Offers Broadest Spectrum of Expert Medical Opinion in Pulmonary Hypertension

This issue of Advances in Pulmonary Hypertension renews our commitment to the pulmonary hypertension community to provide valuable, timely, peer-reviewed scientific information relevant to clinical practice. Beginning with its first issue more than 3 years ago, the journal has embodied a team effort. Reflecting the fact that pulmonary hypertension is a complex disease, our editorial focus has been derived from experts whose areas of concentration reflect the diverse nature of this disorder and its complications.

As I assume the role of Editor-in-Chief, I pursue the same strategy because it has served us well. We will continue to build on a team effort of national and international experts whose goal is to find a cure for pulmonary hypertension. While the cure remains elusive, we are finding significant ways to improve the quality of life of patients with the disease; the journal serves as a chronicle of that story as it focuses on important developments in translational research and relates them to clinical considerations and decisions.

We are challenged by and appreciative of the leadership provided during the first 3 years of publication. We gratefully acknowledge the hard work and guidance provided by Victor F. Tapson, MD, Editor-in-Chief during this time. His contribution to the launch of the journal has left us with a solid foundation on which to build. His high editorial standards give us a legacy to live up to and the enthusiastic response to the journal from 30,000 readers makes us proud of Vic’s contribution. We are also grateful for the guidance provided by the Editorial Advisory Board of Richard N. Channick, MD, Sean Gaine, MD, PhD, Ronald J. Oudiz, MD, and Ivan M. Robbins, MD. The help from these leading academicians in identifying appropriate topics, participating in roundtable discussions and ensuring the overall quality of content inspires us to continue their excellent work.

With this issue, you will see more evidence of our team approach to pulmonary hypertension. Drs Channick and Oudiz will remain as Associate Editors, and we have added Ramona Doyle, MD, Karen Fagan, MD, and Oliver Sitbon, MD. Our Editorial Advisory Board has been expanded because more physicians have expressed a special interest in the journal and we look forward to working with them throughout the year as they participate in the editorial process. These physicians include: Gregory Ahearn, MD, Jacques Benisty, MD, Raymond Benza, MD, Erika Berman-Rosenzweig, MD, Todd Bull, MD, Murali Chakinala, MD, Jeffrey Edelman, MD, Jim Maloney, MD, Robert Schiltz, DO, and Roxana Sulica, MD. (read more...)

Vallerie V. McLaughlin, MD
Editor-in-Chief

 

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Articles
 
Advances in Pulmonary Hypertension, Spring 2005, Vol. 4, No. 1

Click titles to read stories...

Profiles in Pulmonary Hypertension:
Jim Loyd, MD: Probing Early Mysterious Deaths in Families, Jim Loyd, MD, Helps Solve Riddle of Genetic Mutation in PPH Soon after a 30-year-old woman with primary pulmonary hypertension (PPH) was referred to Jim Loyd, MD, the first pieces of a huge and complex puzzle began falling into place....

Defining the Role and Clinical Relevance of BMPR2 Mutations In Pulmonary Arterial Hypertension: Recent advances in molecular genetics during the past four years have defined two genes that causally underlie the development of pulmonary arterial hypertension.

TGF-beta Receptors in Pulmonary Arterial Hypertension: The HHT Connection: Substantial progress in delineating the molecular and genetic basis of pulmonary arterial hypertension has placed the TGFbeta cell-signaling pathway as the centerpiece of contemporary thinking about the pathogenesis of this disorder.

The Serotonin Pathway in Pulmonary Hypertension: The effects of serotonin (5-hydroxytryptamine, 5-HT) on the pulmonary circulation have been investigated because of the reported increased risk of idiopathic pulmonary arterial hypertension (IPH) in patients who used appetite suppressants that interact with 5-HT.

Potential Genetic Contributions to Nonidiopathic, Nonfamilial Pulmonary Hypertension: The recent Venice Classification of pulmonary hypertension1 includes diseases that are definitely or possibly genetic and associated with the development of pulmonary hypertension.

The Future of Genetics in Pulmonary Arterial Hypertension: Research into the genetic basis of pulmonary arterial hypertension is going forward with increasing intensity. It appears that mutations in bone morphogenetic protein receptor type II (BMPR2) and activin receptor-like kinase-1 (ALK1) genes will be the most common genetic risk factors for the development of pulmonary arterial hypertension.

 

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Notes
 

Editorial Advisory Board

Editor-in-Chief
Richard Channick, MD
Professor of Clinical Medicine
Pulmonary and Critical Care Division
University of California, San Diego Medical Center
San Diego, California

Immediate Past Editor
Ronald J. Oudiz, MD
Associate Professor of Medicine
The David Geffen School of Medicine at UCLA
Director, Liu Center for Pulmonary Hypertension
LA Biomedical Research Institute at Harbor-UCLA Medical Center

Editor-in-Chief Elect
Erika Berman Rosenzweig, MD
Director, Pulmonary Hypertension Center, Columbia University Medical Center Associate Professor of Clinical Pediatrics (in Medicine)

Associate Editors

Kristin Highland, MD
Assistant Professor of Medicine
Division of Pulmonary, Critical Care, Allergy and Sleep Medicine
Medical University Of Carolina

Francisco Soto, MD, MS
Director, Pulmonary Hypertension Program
Pulmonary and Critical Care Medicine
Medical College of Wisconsin

Todd Bull, MD
Associate Professor of Medicine
Division of Pulmonary Sciences and Critical Care Medicine
University of Colorado Health Sciences Center

Robert Schilz, DO, PhD
Medical Director of Lung
Transplantation and Pulmonary Vascular Disease
University Hospital of Cleveland
Case Western Reserve University
Cleveland, Ohio


Publisher
Pulmonary Hypertension Association
Carl Hicks, Board Chair
Rino Aldrighetti, President
Sherrie Borden, Vice President, Medical and Patient Education

Publishing Staff
Managing Editor
Deborah L. McBride
McBride Strategic Services
mcbridedeb@aol.com
P: 773-348-5455
C: 312-307-5455
Design Director
Michael McClain

PHA Office
Pulmonary Hypertension Association
801 Roeder Road, Ste. 400
Silver Spring, MD 20910
301-565-3004, 301-565-3994 (fax)
www.PHAssociation.org

© 2009 by Pulmonary Hypertension Association. All rights reserved. None of the contents may be reproduced in any form whatsoever without the written permission of PHA.

Advances in Pulmonary Hypertension is circulated to cardiologists, pulmonologists, rheumatologists and other selected physicians by the Pulmonary Hypertension Association. The contents of the articles are independently determined by the Editor and the Editorial Advisory Board.

PHA's Scientific Leadership Council

Editorial Mission
Advances in Pulmonary Hypertension is committed to help physicians in their clinical decision making by informing them of important trends affecting their practice. Analyzing the impact of new findings and covering current information in the peer-reviewed literature, Advances in Pulmonary Hypertension is published four times a year. Advances in Pulmonary Hypertension is the official journal of the Pulmonary Hypertension Association.

Each article in this journal has been reviewed and approved by members of the Editorial Advisory Board.
 

Editorial Board

Charles Burger, MD
Medical Director, PH Clinic
Mayo Clinic
Jacksonville, FL

Karen Fagan, M.D.
Chief, Division of Pulmonary and Critical Care Medicine University of South Alabama

Eli Gabbay, MD
Lung Transplant Unit
Royal Perth Hospital

Nick Kim, M.D.
Associate Clinical Professor of Medicine
University of California San Diego

Deborah Jo Levine, M.D.
University of Texas Health Science Center at San Antonio
San Antonio, TX

Omar Minai, MD
Dept of Pulmonary, Allergy  and Critical Care Medicine

Myung Park, MD
Associate Professor of Medicine
Division of Pulmonary Sciences and Critical Care Medicine
University of Colorado Health Sciences Center

Fernando Torres, MD
Director Pulmonary Hypertension Clinic
UTSW Medical Center Dallas
University Hospital

Glenna Traiger, RN, MSN
Pulmonary & Critical Care
Pulmonary Hypertension CNS
University of California Los Angeles
Los Angeles, CA

R. James White, MD, PhD
Assistant Professor of Medicine, Pharmacology & Physiology
University of Rochester, Division of Pulmonary and CCM

Roham Zamanian, MD
Division of Pulmonary and Critical Care Medicine
Stanford University Medical Center

 

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