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Summer 2004, Vol. 3, No. 2

Editor’s Memo   For the first time in its history the Pulmonary Hypertension Association’s international conference will include a scientific program for physicians, researchers, and nurses. Featuring internationally known experts, the scientific program is entitled, From Puzzle to Picture—Mechanisms of PH: Identification of the Next Therapeutic Targets, June 24-25 in Miami, Florida. Co-sponsored by the National Heart, Lung, and Blood Institute (NIH), the Centers for Disease Control and Prevention (CDC) and the Office of Rare Diseases (ORD), the program will include poster sessions, abstracts, and workshops as it consolidates recent basic and investigational advances to develop a consensus structure for further investigation. My colleagues and I on the Scientific Leadership Council are excited about the opportunity to meet in a forum that will bring together our peers from throughout the country in the spirit of scientific inquiry. After this meeting, physicians, researchers and nurses can take advantage of the patient-oriented conference, June 25-27 at which more than 50 medical and patient-led sessions will be held. The establishment of the Scientific Sessions means that we have developed an exciting and much needed venue in which to carry on the dialogue with our peers, providing a connection for physicians and doctorate- level researchers with a special interest in PH to meet with key opinion leaders whose investigative work is paving the way for advances in identifying the mechanisms of PH, and hopefully appropriate therapeutic targets. The sessions will facilitate an improved exchange of information, setting the stage for new multicenter clinical trials spearheaded by the Scientific Leadership Council. For physicians unable to attend the conference, however, we will be providing comprehensive coverage of the highlights of the meeting in the next issue of Advances in Pulmonary Hypertension, including a Roundtable Discussion by members of the Editorial Advisory Board. The coverage will include topics such as the role of ion channels in pulmonary arterial hypertension (PAH), the role of serotonin in PAH, cellular biology of PAH, the genetics of PAH, the role of BMPR in PAH, whether genetic mechanisms can impact upon therapy and future directions in therapy. As PHA has suggested in its literature in advance of the event,“Come to Miami for the Science. . . Stay for the Experience.” Victor F. Tapson, MD Editor-in-Chief   Take it With You   Download this issue in PDF (1.52 MB)   Issue Sponsor Ads   Actelion (PDF) Accredo Therapeutics(PDF)	Articles   Advances in Pulmonary Hypertension, Summer 2004, Vol. 3, No. 2 cover close-up Click titles to read stories... Profiles in Pulmonary Hypertension: Michael D. McGoon, MD: Guiding Light for PHA Scientific Leadership Council and Proponent of New Research ...One of the catalysts behind that effort is Michael D. McGoon, MD, current chair of the Council, whose guidance and exemplary leadership has earned him wide recognition in the pulmonary hypertension community.... Portopulmonary Hypertension: Understanding Pulmonary Hypertension in the Setting of Liver Disease A relationship between the liver and lung was proposed by the Greek physician Galen (AD c. 126-216), who believed that venous blood was “concocted in the liver,” migrated via a tidal motion to the right ventricle of the heart, and divided into two blood streams, one to the lungs and one through the heart into the left ventricle.... Liver Transplant Considerations and Outcomes for the Portopulmonary Hypertension Patient The perioperative management of patients presenting for orthotopic liver transplantation who have associated pulmonary hypertension still presents a challenge to the operative team.... Pulmonary Hypertension Roundtable Exploring the Spectrum of Pathology and Treatment in Portopulmonary Hypertension: Four Experts Address the Toughest Questions Featuring: Ronald J. Oudiz, MD, Associate Professor of Medicine, David Geffen School of Medicine, UCLA Director, Liu Center for Pulmonary Hypertension Division of Cardiology Harbor-UCLA Medical Center Torrance, California Michael J. Krowka, MD Professor of Medicine Mayo Clinic Rochester, Minnesota Russell Wiesner, MD Division of Pulmonary and Critical Care Medicine Mayo Clinic Rochester, Minnesota Michael Ramsay, MD, FRCA Chairman, Department of Anesthesiology and Pain Management - Baylor University Medical Center Clinical Professor, Department of Anesthesiology and Pain Management - University of Texas Southwestern Medical Center Dallas, Texas Pull-Out Sections Screening and Diagnostic Algorithm for Portopulmonary Hypertension (PDF) Decision Tree: Management of Pulmonary Hypertension Diagnosed at Induction of Anesthesia for Liver Transplantation. (PDF)   PHA Announcements   PH Doctor: A new professional section within PHA for physicians and MD/PhD-level researchers interested in pulmonary hypertension (PDF) (HTML) New PH Practice Guidelines from the ACCP (PDF) (HTML)
Notes   Editorial Advisory Board Editor-in-Chief Ronald J. Oudiz, MD Associate Professor of Medicine UCLA School of Medicine Director, Liu Center for Pulmonary Hypertension Division of Cardiology Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center Torrance, California Immediate Past Editor Vallerie V. McLaughlin, MD Associate Professor of Medicine Director, Pulmonary Hypertension Program University of Michigan Health System Ann Arbor, Michigan Editor-in-Chief Elect Richard Channick, MD Professor of Clinical Medicine Pulmonary and Critical Care Division University of California, San Diego Medical Center San Diego, California Associate Editors Erika Berman Rosenzweig, MD Assistant Professor of Pediatrics Department of Pediatrics Columbia College of Physicians and Surgeons New York, New York Robert Frantz, MD Consultant in Cardiovascular Diseases and Internal Medicine Assistant Professor of Medicine Mayo Clinic College of Medicine Rochester, Minnesota Srinivas Murali, MD, FACC Professor of Medicine Drexel University College of Medicine Director, Division of Cardiovascular Medicine Medical Director, Gerald McGinnis Cardiovascular Institute Allegheny General Hospital Pittsburgh, Pennsylvania Publisher Pulmonary Hypertension Association Jack Stibbs, Board Chair Rino Aldrighetti, President Donica Merhazion, Medical Services Associate Director Publishing Staff Stu Chapman, Executive Editor Susan Chapman, Managing Editor Heidi Green, Associate Editor Gloria Catalano, Production Director Michael McClain, Design Director PHA Office Pulmonary Hypertension Association 801 Roeder Road., St.e 400 Silver Spring, MD 20910 301-565-3004, 301-565-3994 (fax) www.PHAssociation.org Provided with an unrestricted educational grant from Actelion Pharmaceuticals, U.S., Inc. and Accredo Therapeuticss. © 2006 by Pulmonary Hypertension Association and DataMedica. All rights reserved. None of the contents may be reproduced in any form whatsoever without the written permission of PHA. Editorial Offices Advances in Pulmonary Hypertension DataMedica 424 Dune Road Westhampton Beach, NY 11978 Tel: 631-288-7733 Fax: 631- 288-7744 Advances in Pulmonary Hypertension is circulated to cardiologists, pulmonologists, rheumatologists and other selected physicians by the Pulmonary Hypertension Association . The contents of the articles are independently determined ly the Editor and the Editorial Advisory Board. PHA's Scientific Leadership Council Editorial Mission Advances in Pulmonary Hypertension is committed to help physicians in their clinical decision making by informing them of important trends affecting their practice. Analyzing the impact of new findings and covering current information in the peer-reviewed literature, Advances in Pulmonary Hypertension is published four times a year. Advances in Pulmonary Hypertension is the official journal of the Pulmonary Hypertension Association. Each article in this journal has been reviewed and approved by members of the Editorial Advisory Board.   Editorial Board Todd Bull, MD Division of Pulmonary Sciences and Critical Care Medicine University of Colorado Health Sciences Center Denver, Colorado Murali Chakinala, MD Director, Pulmonary Hypertension Clinic Washington University School of Medicine St. Louis, Missouri Kristin Highland, MD Assistant Professor Division of Pulmonary and Critical Care Director, Pulmonary Hypertension Clinic Medical University of South Carolina Charleston, South Carolina Jim Maloney, MD Associate Professor of Pulmonary and Critical Care Medicine University of Colorado Health Sciences Center Denver, Colorado Ioana Preston, MD Assistant Professor of Medicine Tufts - New England Medical Center Boston, Massachusetts Zeenat Safdar, MD Assistant Professor of Medicine Department of Medicine, Pulmonary & Critical Care Section Pulmonary Hypertension Center Baylor College of Medicine Houston, Texas Rajan Saggar, MD Assistant Professor Division of Pulmonary and Critical Care Medicine and Hospitalists David Geffen School of Medicine UCLA Los Angeles, California Robert Schilz, DO, PhD Medical Director of Lung Transplantation and Pulmonary Vascular Disease University Hospital of Cleveland Case Western Reserve University Cleveland, Ohio Francisco Soto, MD, MS Assistant Professor Director, Pulmonary Hypertension Program Medical College of Wisconsin Milwaukee, Wisconsin Roxana Sulica, MD Assistant Professor of Medicine Albert Einstein College of Medicine Director, Beth Israel Pulmonary Hypertension Program Beth Israel Medical Center New York, New York

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