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Summer 2005, Vol. 4, No. 2

Editor’s Memo
 

ATS Meeting Serves as Useful Measure
Of Rising Interest in Pulmonary Hypertension

This year’s meeting of the American Thoracic Society (ATS) was exciting from several vantage points, including the fact that it was the 100th anniversary of the ATS, a striking achievement for this venerable organization. The ATS meeting is the largest gathering of pulmonary and critical care specialists in the world. For those of us
involved with or closely following developments in pulmonary hypertension
(PH), the meeting was also notable because of the extensive focus devoted to PH at this meeting, in scientific sessions, debates,
abstracts, and original research. As a moderator for some of these sessions, I was fortunate enough to personally become part of the lively and challenging discussions, including the controversies that fueled the debates.

Evidence of the growing interest in PH at this meeting can be quantified if one likes to keep track statistically of such trends. The ATS web site, for example, lists 322 abstracts on PH alone. This number is a good barometer for the rising interest in PH, especially when one considers that in 2004 the ATS had 272 abstracts on PH featured in its program. One of the abstracts in the 2005 session concerning the relationship of hypoxemia to pulmonary artery pressure in pulmonary arterial hypertension (PAH) was presented by Duke University investigators, including Victor F. Tapson, MD, my predecessor as Editor-in-Chief of Advances in Pulmonary Hypertension,
and his colleague, Richard C. Redman, MD.

Although PH associated with hypoxemic lung disease is a common problem, it is
one of those areas where we need more information to more precisely identify how it should be classified. As their abstract and poster pointed out, little data exist regarding hypoxemia in patients with PAH. While it might appear intuitive, a clear correlation between hypoxemia and pulmonary artery pressure in this disease has not been
shown, yet further characterization of this relationship may provide insight into the pathophysiology and clinical manifestations of PAH. As the conclusion notes:
patients with severe PAH were significantly more hypoxemic than patients with mild to moderate PAH. Drs Tapson and Redman conclude that hypoxemia is generally more pronounced as PAH becomes more severe and may be more important in the pathophysiology of PAH than previously appreciated.

For more insights on this relationship, I encourage readers to review the information in an article by Robert Schilz, DO, PhD, in this issue, as well as the Roundtable discussion chaired by Richard Channick, MD. We would like to express our appreciation to Dr Channick for serving as the Guest Editor of this issue and bringing together the editorial content focusing on PH associated with lung diseases.

Vallerie V. McLaughlin, MD
Editor-in-Chief

 
Articles
 
Advances in Pulmonary Hypertension, Summer 2005, Vol. 4, No. 2

Click titles to read stories...

Profiles in Pulmonary Hypertension:
John West, MD: Climbing With Dr John West in the Rarefied Air of Pulmonary Research: From Mount Everest to the University of California, San Diego
When you have been recruited as a clinical investigator to climb Mount Everest with Sir Edmund Hillary, have coauthored 427 articles and 21 books,... what worlds are left to conquer? Quite a few, says John West, MD...

Pulmonary Hypertension Due to Respiratory Disease: Pathogenesis and Diagnostic Approach: Since the discovery of hypoxic pulmonary vasoconstriction six decades ago, respiratory physiologists and clinicians have been fascinated by pulmonary hypertension in the setting of chronic lung disease.

The New UNOS Lung Transplantation Allocation System: Lung or heart-lung transplantation is an acceptable therapeutic option for patients with advanced lung diseases, including patients with pulmonary hypertension in whom all other therapies have been exhausted. However, the supply of donor lungs is scarce relative to the demand.

Treatment of Pulmonary Hypertension Related to Disorders of Hypoxia: As part of an ongoing series of articles on the evaluation and management of pulmonary hypertension, this article will address issues in the treatment of pulmonary hypertension related to hypoxemia.

Pulmonary Hypertension Roundtable

Pulmonary Hypertension in Lung/Respiratory Disease: How Important? What to Do?

 

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Notes
 

Editorial Advisory Board

Editor-in-Chief
Richard Channick, MD
Professor of Clinical Medicine
Pulmonary and Critical Care Division
University of California, San Diego Medical Center
San Diego, California

Immediate Past Editor
Ronald J. Oudiz, MD
Associate Professor of Medicine
The David Geffen School of Medicine at UCLA
Director, Liu Center for Pulmonary Hypertension
LA Biomedical Research Institute at Harbor-UCLA Medical Center

Editor-in-Chief Elect
Erika Berman Rosenzweig, MD
Director, Pulmonary Hypertension Center, Columbia University Medical Center Associate Professor of Clinical Pediatrics (in Medicine)

Associate Editors

Kristin Highland, MD
Assistant Professor of Medicine
Division of Pulmonary, Critical Care, Allergy and Sleep Medicine
Medical University Of Carolina

Francisco Soto, MD, MS
Director, Pulmonary Hypertension Program
Pulmonary and Critical Care Medicine
Medical College of Wisconsin

Todd Bull, MD
Associate Professor of Medicine
Division of Pulmonary Sciences and Critical Care Medicine
University of Colorado Health Sciences Center

Robert Schilz, DO, PhD
Medical Director of Lung
Transplantation and Pulmonary Vascular Disease
University Hospital of Cleveland
Case Western Reserve University
Cleveland, Ohio


Publisher
Pulmonary Hypertension Association
Carl Hicks, Board Chair
Rino Aldrighetti, President
Sherrie Borden, Vice President, Medical and Patient Education

Publishing Staff
Managing Editor
Deborah L. McBride
McBride Strategic Services
mcbridedeb@aol.com
P: 773-348-5455
C: 312-307-5455
Design Director
Michael McClain

PHA Office
Pulmonary Hypertension Association
801 Roeder Road, Ste. 400
Silver Spring, MD 20910
301-565-3004, 301-565-3994 (fax)
www.PHAssociation.org

© 2009 by Pulmonary Hypertension Association. All rights reserved. None of the contents may be reproduced in any form whatsoever without the written permission of PHA.

Advances in Pulmonary Hypertension is circulated to cardiologists, pulmonologists, rheumatologists and other selected physicians by the Pulmonary Hypertension Association. The contents of the articles are independently determined by the Editor and the Editorial Advisory Board.

PHA's Scientific Leadership Council

Editorial Mission
Advances in Pulmonary Hypertension is committed to help physicians in their clinical decision making by informing them of important trends affecting their practice. Analyzing the impact of new findings and covering current information in the peer-reviewed literature, Advances in Pulmonary Hypertension is published four times a year. Advances in Pulmonary Hypertension is the official journal of the Pulmonary Hypertension Association.

Each article in this journal has been reviewed and approved by members of the Editorial Advisory Board.
 

Editorial Board

Charles Burger, MD
Medical Director, PH Clinic
Mayo Clinic
Jacksonville, FL

Karen Fagan, M.D.
Chief, Division of Pulmonary and Critical Care Medicine University of South Alabama

Eli Gabbay, MD
Lung Transplant Unit
Royal Perth Hospital

Nick Kim, M.D.
Associate Clinical Professor of Medicine
University of California San Diego

Deborah Jo Levine, M.D.
University of Texas Health Science Center at San Antonio
San Antonio, TX

Omar Minai, MD
Dept of Pulmonary, Allergy  and Critical Care Medicine

Myung Park, MD
Associate Professor of Medicine
Division of Pulmonary Sciences and Critical Care Medicine
University of Colorado Health Sciences Center

Fernando Torres, MD
Director Pulmonary Hypertension Clinic
UTSW Medical Center Dallas
University Hospital

Glenna Traiger, RN, MSN
Pulmonary & Critical Care
Pulmonary Hypertension CNS
University of California Los Angeles
Los Angeles, CA

R. James White, MD, PhD
Assistant Professor of Medicine, Pharmacology & Physiology
University of Rochester, Division of Pulmonary and CCM

Roham Zamanian, MD
Division of Pulmonary and Critical Care Medicine
Stanford University Medical Center

 

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