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Medical Journal

Winter 2004, Vol. 3, No. 4

Editor’s Memo
 

Under the Tent of the New ACCP Guidelines in PAH: Room for Debate, Comment, Analysis

Publication of the new American College of Chest Physicians (ACCP) evidence-based clinical practice guidelines for pulmonary arterial hypertension (PAH) represents a major advance in understanding the diagnosis and management of the disease. For the target audience of cardiologists, pulmonologists, rheumatologists, internists, and other healthcare providers involved in such care, the guidelines are the first revision of an earlier document created 10 years ago. Lewis J. Rubin, MD, who chaired the consensus panel, and the international panel of 19 experts from five medical specialties, deserve our appreciation and praise for the extraordinary work they have done during the last 3 years. We applaud their efforts and commitment to the highest standards of medical care.

If the guidelines cast a long shadow over our practice because of how large they loom in clinical decision-making, they also shed tremendous light on areas where we need more evidence-based information. Under the tent of the guidelines, however, there is plenty of room for debate and comment over how the new criteria should be applied in the myriad decisions we make every day. As clinicians, we must often make decisions in areas in which the evidence base is inadequate because of the need for more data. As our Editorial Board reviewed the guidelines, we wanted to explore various approaches taken by clinicians involved with PAH, especially in areas where the guidelines cannot (of necessity) make strong recommendations.

The experts we have assembled for this issue are not debating the relative merits of the guidelines. Beginning on page 3, they are offering fresh and varied perspectives, whether it is on the use of echocardiography or the benefits of new agents still in phase 3 clinical trials. Gleaned from their own knowledge and practice-based experience, these comments, queries, and insights will, it is hoped, broaden our base of knowledge.

Victor F. Tapson, MD
Editor-in-Chief

 

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Articles
 
Advances in Pulmonary Hypertension, Winter 2004, Vol. 3, No. 4

Click titles to read stories...

Profiles in Pulmonary Hypertension:
Lewis Rubin, MD: From ACCP Guidelines to Pharmacogenomics of PH, Lewis Rubin, MD, Stands Tall as a Prime Mover
Lewis J. Rubin, MD, is one of a select group of physicians who have seen pulmonary hypertension from many different perspectives, one of a handful of clinicians worldwide whose experience spans more than 20 years in this clinical setting. Their experience covers a dramatic ...

Pulmonary Arterial Hypertension: Diagnostic Considerations

Echocardiography

The Role of Electrocardiography

Implantable Hemodynamic Monitoring

Cardiopulmonary Exercise Testing

Pulmonary Arterial Hypertension: Therapeutic Considerations

Calcium-Channel Blockers

Treating Class II PAH Patients

Treating Class III PAH Patients

Treatment for Class IV Patients

Considering Sildenafil

Relative Merits of Different Endothelin Antagonists

Discontinuing Epoprostenol

When to Use Treprostinil

PAH Treatment in Germany

Combination Therapy

Treatment Options in Portopulmonary Hypertension

Severe PH Associated with LVDD

Examining the Use of Anticoagulants

 

 
 

PHA Announcements
 

PH Doctor
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PH Practice Guidelines from the ACCP
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Cardiovascular
Medical Research and Education Fund
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Program Announcement: Mentored Clinical Scientist Development Award (K08) &
Mentored Patient-Oriented Research Career Development Award (K23)
(PDF)

 

   
Notes
 

Editorial Advisory Board

Editor-in-Chief
Richard Channick, MD
Professor of Clinical Medicine
Pulmonary and Critical Care Division
University of California, San Diego Medical Center
San Diego, California

Immediate Past Editor
Ronald J. Oudiz, MD
Associate Professor of Medicine
The David Geffen School of Medicine at UCLA
Director, Liu Center for Pulmonary Hypertension
LA Biomedical Research Institute at Harbor-UCLA Medical Center

Editor-in-Chief Elect
Erika Berman Rosenzweig, MD
Director, Pulmonary Hypertension Center, Columbia University Medical Center Associate Professor of Clinical Pediatrics (in Medicine)

Associate Editors

Kristin Highland, MD
Assistant Professor of Medicine
Division of Pulmonary, Critical Care, Allergy and Sleep Medicine
Medical University Of Carolina

Francisco Soto, MD, MS
Director, Pulmonary Hypertension Program
Pulmonary and Critical Care Medicine
Medical College of Wisconsin

Todd Bull, MD
Associate Professor of Medicine
Division of Pulmonary Sciences and Critical Care Medicine
University of Colorado Health Sciences Center

Robert Schilz, DO, PhD
Medical Director of Lung
Transplantation and Pulmonary Vascular Disease
University Hospital of Cleveland
Case Western Reserve University
Cleveland, Ohio


Publisher
Pulmonary Hypertension Association
Carl Hicks, Board Chair
Rino Aldrighetti, President
Sherrie Borden, Vice President, Medical and Patient Education

Publishing Staff
Managing Editor
Deborah L. McBride
McBride Strategic Services
mcbridedeb@aol.com
P: 773-348-5455
C: 312-307-5455
Design Director
Michael McClain

PHA Office
Pulmonary Hypertension Association
801 Roeder Road, Ste. 400
Silver Spring, MD 20910
301-565-3004, 301-565-3994 (fax)
www.PHAssociation.org

© 2009 by Pulmonary Hypertension Association. All rights reserved. None of the contents may be reproduced in any form whatsoever without the written permission of PHA.

Advances in Pulmonary Hypertension is circulated to cardiologists, pulmonologists, rheumatologists and other selected physicians by the Pulmonary Hypertension Association. The contents of the articles are independently determined by the Editor and the Editorial Advisory Board.

PHA's Scientific Leadership Council

Editorial Mission
Advances in Pulmonary Hypertension is committed to help physicians in their clinical decision making by informing them of important trends affecting their practice. Analyzing the impact of new findings and covering current information in the peer-reviewed literature, Advances in Pulmonary Hypertension is published four times a year. Advances in Pulmonary Hypertension is the official journal of the Pulmonary Hypertension Association.

Each article in this journal has been reviewed and approved by members of the Editorial Advisory Board.
 

Editorial Board

Charles Burger, MD
Medical Director, PH Clinic
Mayo Clinic
Jacksonville, FL

Karen Fagan, M.D.
Chief, Division of Pulmonary and Critical Care Medicine University of South Alabama

Eli Gabbay, MD
Lung Transplant Unit
Royal Perth Hospital

Nick Kim, M.D.
Associate Clinical Professor of Medicine
University of California San Diego

Deborah Jo Levine, M.D.
University of Texas Health Science Center at San Antonio
San Antonio, TX

Omar Minai, MD
Dept of Pulmonary, Allergy  and Critical Care Medicine

Myung Park, MD
Associate Professor of Medicine
Division of Pulmonary Sciences and Critical Care Medicine
University of Colorado Health Sciences Center

Fernando Torres, MD
Director Pulmonary Hypertension Clinic
UTSW Medical Center Dallas
University Hospital

Glenna Traiger, RN, MSN
Pulmonary & Critical Care
Pulmonary Hypertension CNS
University of California Los Angeles
Los Angeles, CA

R. James White, MD, PhD
Assistant Professor of Medicine, Pharmacology & Physiology
University of Rochester, Division of Pulmonary and CCM

Roham Zamanian, MD
Division of Pulmonary and Critical Care Medicine
Stanford University Medical Center

 

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