ASSOCIATED Medical Conditions

Anna Bower, who has pulmonary hypertension, lupus and scleroderma, with her three niecesAnna Bower, who has pulmonary hypertension,
lupus and scleroderma, with her three nieces

Many pulmonary hypertension patients are diagnosed with PH in association with one or more related conditions. Research shows that up to 30% of scleroderma patients, 20-40% of sickle cell patients and one out of every 200 HIV patients develop at least mild PH.

Other conditions commonly associated with PH include mixed connective-tissue disease, congenital heart disease (CHD), chronic obstructive pulmonary disease (COPD), hereditary hemorrhagic telangiectasia (HHT), sleep apnea, liver disease and lupus. PH has also been linked to the use of certain drugs and toxins, including fenfluramine, dexfenfluramine and methamphetamines.

Learn more about PH and…

Visit PHA's full Associated Diseases section

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Symptoms of PH

  • Breathlessness on exertion
  • Chest pain (also called angina pectoris)
  • Dizziness upon standing, climbing stairs, straightening up from a bent position, or even while just sitting
  • Fainting (also called syncope)
  • Loss of energy
  • Swollen ankles and legs (also called edema)
  • Depression
  • Dry cough
  • Raynaud’s Phenomenon (chalky white and/or dusky blue fingers that may be painful and can sometimes be provoked by the cold)

Learn more about the symptoms of PH

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The National Organization for Rare Disorders (NORD) awarded PHA the Abbey S. Meyers Leadership Award in 2012 for outstanding service to PHA members in advocacy, education and other key areas.