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Recapping Highlights from the
Third World Symposium on Pulmonary Arterial Hypertension,
Venice, Italy, June 23-25, 2003
As the broad range of topics suggests, the Third World
Symposium on Pulmonary Arterial Hypertension (PAH) addressed
many of the issues of overriding importance to clinicians
involved with treatment of the disease. Held in Venice,
Italy, from June 23 to 25, the symposium attracted key
opinion leaders from Europe and the United States whose
research has put them on the frontier of advances in PAH.
The symposium assigned topics to various task forces that
met and worked toward a consensus document for key issues,
such as appropriate diagnostic algorithms, functional
capacity tests, and the use of echocardiography and other
noninvasive tests.
The summaries presented in this issue highlight many
of the trends observed by task force members in Venice
and suggest future directions for research in PAH. The
World Symposium on Pulmonary Arterial Hypertension has
helped formulate definitions and classifications that
contribute toward an improved understanding of the pathophysiology
of PAH and have produced algorithms that help guide treatment
strategies. A list of the task force members follows along
with the topics assigned to them:
This listing of physicians indicates who attended
the Third World Symposium on Pulmonary Hypertension and
the Task Forces to which they were assigned as groups
worked toward a consensus on selected topics. The Scientific
Organizing Committee included three physicians in Europe
and three in the United States. In Europe: Nazzareno Galiè,
Bologna, Italy, Werner Seeger, Giessen, Germany, and Gérald
Simonneau, Clamart, France. In the US, the committee included
Robyn J. Barst, New York, New York, Stuart Rich, Chicago,
Illinois, and Lewis J. Rubin, La Jolla, California.
Task Force on Pathology and Pathobiology
Committee: Chairman and Secretary: Marc
Humbert, France
Chairs: Giuseppe Pietra, Switzerland;
Marlene Rabinovitch, Stanford, California; Norbert F.
Voelkel, Denber, Colorado. Members: Stephen L. Archer,
Edmonton, Canada; Frederique Capron, Paris, France; Brian
Christman, Nashville, Tennessee; Friedrich Grimminger,
Giessen, Germany; Sheila G. Haworth, London, UK; Phillipe
Hérvé, Le Plessis Robinson, France; Irene Lang, Vienna,
Austria; Ornella Leone, Bologna, Italy; Margaret R. MacLean,
Glasgow, UK; Nick W. Morrell, Cambridge, UK; Lynne M.
Reid, Boston, Massachusetts; Kurt Stenmark, Denver, Colorado;
Susan Stewart, Cambridge, UK; Rubin Tuder, Baltimore,
Maryland; and E. Kenneth Weir, Minneapolis, Minnesota.
Task Force on Genetics Committee: Chairman and Secretary:
Gregory Elliott, Salt Lake City, Utah; Chairs: John H.
Newman, Nashville, Tennessee; and Richard C. Trembath,
Leicester, UK. Members: Serge Adnot, Cretail, Fraqnce;
Fabio Coccolo, Bologna, Italy; Oliver Eickelberg, Giessen,
Germany; Ekkehard Gruenig, Heidelberg, Germany; James
A. Knowles, New York, New York; James E. Loyd, Nashville,
Tennessee; Jane H. Morse, New York, New York; William
C. Nichols, Cincinnati, Ohio; John A. Phillips III, Nashville,
Tennessee; Werner Seeger, Giessen, Germany; and Carlo
Ventura, Sassari, Italy. Task Force on Epidemiology, Nomenclature
and Classification Committee: Chairman and Secretary:
Gérald Simonneau, Clamart, France; Chairs: Lucien Abenhaim,
Paris, France; Alfred P. Fishman, Philadelphia, Pennsylvania.
Members: Guido Domenighetti, Locarno, Switzerland; Nazzareno
Galiè, Bologna, Italy; Simon Gibbs, London, UK; Miguel
A. Gomez-Sanchez, Madrid, Spain; David Langleben, Montreal,
Canada; Didier Lebrec, Clichy, France; Nick W. Morrell,
Cambridge, UK; Robert Naeije, Brussels, Belgium; Stuart
Rich, Chicago, Illinois; Lewis J. Rubin, La Jolla, California;
Werner Seeger, Giessen, Germany; and Rudolf Speich, Zurich,
Switzerland. Task Force on Diagnosis and Assessment Committee:
Chairman and Secretary: Robyn J. Barst, New York, NY;
Chairs: Michael D. McGoon, Rochester, Minnesota; Adam
Torbicki, Warsaw, Poland.
Members: Joan Albert Barbera, Barcelona, Spain;
Richard N. Channick, La Jolla, California; Gerry Coghlan,
London, UK; Marion Delcroix, Leuven, Belgium; Peter F.
Fedullo, La Jolla, California; Adaani E. Frost, Houston,
Texas; Sean P. Gaine, Dublin, Ireland; Ardeschir Ghofrani,
Giessen, Germany; Marius M. Hoeper, Hannover, Germany;
Marc Humbert, Clamart, France; Meinhard Kneussel, Vienna,
Austria; Michael J. Krowka, Rochester, Minnesota; Alessandra
Manes, Bologna, Italy; Horst Olschewswki, Giessen, Germany;
Ronald J.Oudiz, Torrance, California; Andrew J. Peacock,
Glasgow, UK; Joanna Pepke-Zaba, Cambridge, UK; Ivan M.
Robbins, Nashville, Tennessee; Olivier Sitbon, Clamart,
France; Victor F. Tapson, Durham, North Carolina; Jean-Luc
Vachiéry, Brussels, Belgium; and Carmine Dario Vizza,
Rome, Italy.
Task Force on Medical Treatments Committee:
Chairman and Secretary: Nazzareno Galiè,
Bologna, Italy;
Chairs: Lewis J. Rubin, La Jolla, California;
Werner Seeger, Giessen, Germany. Members:
David B. Badesch, Denver, Colorado; Joan Albert Barbera,
Barcelona, Spain; Robyn J. Barst, New York, New York;
Ardeschir Ghofrani, Giessen, Germany; Sheila G. Haworth,
London, UK; Marius M. Hoeper, Hannover, Germany; Marc
Humbert, Clamart, France; Ann Keogh, Sydney, Australia;
Vallerie V. McLaughlin, Ann Arbor, Michigan; Horst Olschewski,
Giessen, Germany; Ronald J. Oudiz, Torrance, California;
Andrew J. Peacock, Glasgow, UK; Gerald Simonneau, Clamart,
France; Olivier Sitbon, Clamart, France; Gianni Tognoni,
Milan, Italy; and Adam Torbicki, Warsaw, Poland.
Task Force on Interventional and Surgical Treatments
Committee:
Chairman and Secretary: Paul Corris,
Newcastle, UK;
Chairs: Stuart W. Jamieson, San Diego,
California; Walter Klepetko, Vienna, Austria.
Members: Phillipe Dartevelle, Le Plessis Robinson,
France; Peter F. Fedullo, La Jolla, California; Michael
J. Landzberg, Boston, Massachusetts; Irene Lang, Vienna,
Austria; Eckhard Mayer, Mainz, Germany; Joanna Pepke-Zaba,
Cambridge, UK; Julio Sandoval, Mexico City, Mexico; Elbert
P. Trulock, St. Louis, Missouri; Jean-Luc Vachiéry, Brussels,
Belgium.
Task Force on Future Directions Committee:
Chairman and Secretary: Stuart Rich,
Chicago, Illinois;
Chairs: Robert Naeije, Brussels, Belgium;
Andrew J. Peacock, Glasgow, UK. Members:
Brian Christman, Nashville, Tennessee; Gerry Coghlan,
London, UK; Oliver Eickelberg, Giessen, Germany; Sean
P. Gaine, Dublin, Ireland; Friedrich Grimminger, Giessen,
Germany; Tim Higenbottam, Sheffield, UK; Stefan Janssens,
Leuven, Belgium; John H. Newman, Nashville, Tennessee;
Marlene Rabinovitch, Stanford, California; Richard C.
Trembath, Leicester, UK; Norbert F. Voelkel, Denver, Colorado;
and E. Kenneth Weir, Minneapolis, Minnesota.
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