PHA Proof of Concept Award winners

This grant’s target audience is investigators who are interested in early-stage pulmonary hypertension research.

This program supports new research projects that are in the early exploratory and developmental stages and have the potential to lead to advances in the scientific understanding of PH. Proposed projects result in preliminary data that will enable the investigator to apply for support for a larger, hypotheses-driven research project.

As of 2014, PHA has supported 13 researchers through this partnership and we hope to continue to further our understanding of PH by continuing to support such novel efforts in the field.

2014

Daniel L. Fox, MD

Daniel L. Fox, MD
"SSc-PAH Risk Score: Early Identification of Scleroderma-associated PAH by RV Strain, GDF-15 & IL&r"
December 1, 2014 - November 30, 2015
University of Colorado Denver
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Frances S. de Man, PhD

Frances S. de Man, PhD
"A New Tool to Obtain Novel Insights in PAH-Induced Right Heart Failure"
December 1, 2014 - November 30, 2015
VU University Medical Center Amsterdam
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The Jerry Wojciechowski Pulmonary Hypertension Proof of Concept Grant

Fiona Murray, PhD

Fiona Murray, PhD
"A novel G-protein coupled receptor (GPCR) target in pulmonary arterial hypertension"
January 15, 2015 - January 14, 2016
University of Aberdeen, UK
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American Thoracic Society Foundation/Pulmonary Hypertension Association Proof of Concept Research Grant

Marc de Perrot, MD

Marc de Perrot, MD, MSc
"Photodynamic therapy for the treatment of pulmonary arterial hypertension"
December 1, 2014 - November 30, 2015
University of Toronto, Canada
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2013

 

Evan Brittain

Evan L. Brittain, MD
"Cardiac Steatosis and Right Ventricular Failure in Pulmonary Arterial Hypertension"
December 1, 2013 - November 30, 2014
Vanderbilt University School of Medicine, Nashville, Tenn.
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Jiwang Chen

Jiwang Chen, PhD
"Role of IL7/IL7R in the Pathogenesis of Pulmonary Arterial Hypertension"
December 1, 2013 - November 30, 2014
University of Illinois at Chicago, Chicago, Ill.
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Kylie Drake

Kylie M. Drake, PhD
"Pharmacological Correction of BMP Signaling by Read-Through in Pulmonary Arterial Hypertension"
December 1, 2013 - November 30, 2014
The Cleveland Clinic Foundation, Cleveland, Ohio
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The Jerry Wojciechowski Pulmonary Hypertension Proof of Concept Grant

Nicole M. Pohl, PhD

Nicole M. Pohl, PhD
"Role of miR-181b in the Regulation of TRPC6 and the Development of Pulmonary Hypertension"
December 1, 2013 - November 30, 2014
University of Illinois at Chicago, Chicago, Ill.
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Yen-Rei Yu, MD, PhD

Yen-Rei Yu, MD, PhD
"The Role of Resident Monocytes in the Pathogenesis of Pulmonary Arterial Hypertension"
January 15, 2014 - January 14, 2015
Duke University School of Medicine, Durham, N.C.
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2012

 

Michael Yeager, PhD

Michael Yeager, PhD
Unfolded Protein Response Confers Apoptosis Resistance and Inflammation in Pulmonary Hypertension
December 1, 2012 – November 30, 2013
University of Colorado Health Sciences Center, Denver
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Guofei Zhou, PhD

Guofei Zhou, PhD
AMPK and Pulmonary Arterial Hypertension
December 1, 2012 – November 30, 2013
University of Illinois College of Medicine, Chicago
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2011

 

Mary Beth Brown, PhD, PT, ATC

Mary Beth Brown, PhD, PT, ATC
Clinical Investigation of a Daily Walking Program plus L-Arginine Supplementation for the Treatment of Pulmonary Arterial Hypertension
October 1, 2011 – September 30, 2012
Indiana University, Indianapolis
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Ferhaan Ahmad, MD, PhD

Ferhaan Ahmad, MD, PhD
Applying Genomics as a Springboard to Novel Mechanisms of Pulmonary Hypertension
October 1, 2011 – September 30, 2012
University of Pittsburgh, Pittsburgh
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The National Organization for Rare Disorders (NORD) awarded PHA the Abbey S. Meyers Leadership Award in 2012 for outstanding service to PHA members in advocacy, education and other key areas.