RESEARCH IN PULMONARY HYPERTENSION

"PHA's research program has yielded an explosion of understanding about PH that was not known before."
- John Newman, MD, Vanderbilt University Medical Center


Twenty years ago there were no pulmonary hypertension treatments available. Through focused research there are now nine PH-specific treatments with more in development. But we know that your ultimate wish is for a cure, and that is why PHA will continue to support the work of researchers until the day when no one suffers from PH.

PHA’s Research Program

In just a little under a decade, PHA’s Research Program has committed more than $12.5 million for PH research by leveraging partnerships with the National Heart, Lung, and Blood Institute (NHLBI) and the American Thoracic Society (ATS). We have supported over 49 promising researchers through four independently reviewed, cutting-edge research programs.

Read more about PHA’s Research Program

Learn more

Current Treatments

PHA’s Scientific Leadership Council’s Education Committee has put together comprehensive factsheets on all the treatments available for pulmonary hypertension. Read more about current treatments

Research Corner in Pathlight

Every issue of PHA’s quarterly print newsletter Pathlight features a Research Corner with information about some of the latest research. Read more

 

Pulmonary Hypertension Research News
Race, Sex Differences May Affect Response to PAH Drugs

In a recent study analyzing 1,130 patients with PAH who were enrolled in one of the original clinical trials of endothelin receptor antagonists (ERAs), it was found that there were distinct response to treatment between men and women and patients of different race. Read article


Tuesday, March 05, 2013 4:25:00 PM

Fetal Growth Restriction and Pulmonary Hypertension in Premature Infants with Bronchopulmonary Dysplasia

Study findings published in the Journal of Perinatology...

Birth weight for gestational age is an important predictor of pulmonary hypertension in premature infants with moderate to severe bronchopulmonary dysplasia. Our findings contribute to the growing evidence supporting fetal mechanisms of later onset pulmonary vascular disease. Read more


Thursday, January 24, 2013 4:22:00 PM

Relationship Between Serum Uric Acid Levels and Patient Conditions and Prognosis in Idiopathic Pulmonary Arterial Hypertension

Study findings in PubMed.gov...

The serum level of uric acid correlates significantly with patient conditions and prognosis in IPAH. And a higher serum level of uric acid predicts worse conditions and prognosis. Read more


Thursday, January 24, 2013 4:19:00 PM

Link Between Abnormal Bone Marrow Cells and Pulmonary Arterial Hypertension

Investigators have uncovered a new clue to the cause of pulmonary arterial hypertension, a progressive and frequently lethal disease that in many cases arises mysteriously. A report published in June 2012 describes findings suggesting that bone marrow-derived endothelial progenitor cells play a role in causing the vascular injury in the lung that underlies the disease.

This study was released by the National Heart, Lung, and Blood Institute (NHLBI) on a list of their top research findings of 2012. Read More


Thursday, January 17, 2013 2:40:00 PM

Pulmonary Hypertension Could Be Late Effect of Childhood Cancer Therapy

(Doctors Lounge) - Gregory T. Armstrong, MD, of St. Jude Children's Research Hospital in Memphis, Tenn., and colleagues conducted a cross-sectional assessment involving 498 adult survivors of childhood cancer to examine the prevalence of pulmonary hypertension, a late effect of cancer therapy. Read article


Thursday, January 17, 2013 8:55:00 AM

HOW YOU CAN HELP

Woman having blood drawn

Participating in research & clinical trials helps gain information vital to progress toward a cure

Learn more about participating in research

ADVOCATE FOR RESEARCH FUNDING

Put your Members of Congress to work for you, their constituent. Ask them to support federal funding for PH research and education.

Advocate for PH research funding

Email Updates

Stay informed about current research, events, and more.

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Donate to Research

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NORD

The National Organization for Rare Disorders (NORD) awarded PHA the Abbey S. Meyers Leadership Award in 2012 for outstanding service to PHA members in advocacy, education and other key areas.